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What is Klonopin:-
Klonopin is a benzodiazepine with prominent anticonvulsant properties. It blocks PTZ seizures at doses which produce mild sedation. It’s efficacy in modifying maximal electroshock seizures is low and it is singularly ineffective in GTCS.
Benzodiazepines potentiate GABA which induce Chlorine influx to produce sedation and the same mechanism has been held responsible for the anticonvulsant property, but the locus of action in the brain may be different.
It is also highly effective for urgent treatment of acute panic attacks.
Uses of Klonopin:-
Klonopin has been primarily employed in absence seizures. However, its value is limited by development of tolerance to the therapeutic effect within Six months or so. Klonopin is also used to suppress acute mania. It is also used to treat panic attack.
The recommended dose of Klonopin for the adults is of 0.5–5mg 3 times a day.
For children the recommended dose is 0.02-0.2mg/kg/day.
The most important side effect of Klonopin is sedation and dullness.
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